Stéphanie Portet’s research focuses on the mathematical and computational modeling of the cytoskeleton, specifically the intermediate filament network. Her work aims to understand the assembly, network organization, and viscoelastic properties of these structures, which play a crucial role in cell stabilization, migration, and signal transduction. By developing analytical frameworks, she characterizes the complex processes of filament assembly and tests various mechanistic hypotheses. Combining these mathematical modeling approaches with experimental data allows for rigorous validation, offering a powerful tool to investigate cellular biology and the misorganizations linked to various diseases.

Current trainees

  • Clotilde Djuikem. Postdoctoral fellow, Department of Mathematics.
  • Lihini Hiranya Kankanamge. M.Sc. student, Department of Mathematics.

Recent Publications (Past 5 Years)

Within-host immunology to age-of-infection epidemiology via a virtual cohort

Julien Arino , Morgan Craig , Clotilde Djuikem , Kang-Ling Liao , Stéphanie Portet
2026-05-16
0 citations

Using Floquet theory to unravel far-from equilibrium dynamics in reaction–diffusion systems

V. O. Juma , K. Z. Mapfumo , Stéphanie Portet , A. Madzvamuse
PNAS Nexus 2026-03-01

Basic Science and Pathogenesis.

M. E. Keleshteri , Chris Cadonic , T. Ghafourian , Ella Thomson , W. Snow , D. McAllister , J. Djordjevic , S. R. Chowdhury , Paul Fernyhough , J. Fiege , Stéphanie Portet , B. Albensi
Alzheimer's & Dementia 2024-12-01
0 citations

Steady state distributions of moving particles in one dimension: with an eye towards axonal transport

J. Dallon , E. Evans , Christopher P. Grant , Stéphanie Portet
Journal of Mathematical Biology 2024-10-30

Abstract 7381: Mathematical modeling and validation of mechanistic target of rapamycin and N-myristoyltransferase signaling pathways in breast cancer

Abinash Meher , Shailly Varma Shrivastav , Anouska Agarwal , Sheen Dube , Stéphanie Portet , Anuraag Shrivastav
Cancer Research 2024-03-22

Insights into B Cell and Antibody Kinetics Against SARS-CoV-2 Variants Using Mathematical Modelling

S. Farhang-Sardroodi , X. Deng , Stéphanie Portet , Julien Arino , Morgan Craig
bioRxiv 2023-11-12

A simple in-host model for COVID-19 with treatments: model prediction and calibration

Isam Al-Darabsah , Kang-Ling Liao , Stéphanie Portet
Journal of Mathematical Biology 2023-01-10
13 citations

Models of vimentin organization under actin-driven transport.

Youngmin Park , Cécile Leduc , S. Étienne-Manneville , Stéphanie Portet
Physical Review E 2022-09-06
2 citations

Using Fluorescence Recovery After Photobleaching data to uncover filament dynamics

J. Dallon , Cécile Leduc , Christopher P. Grant , E. Evans , S. Étienne-Manneville , Stéphanie Portet
PLoS Comput. Biol. 2022-09-01
6 citations

Dual-wavelength stopped-flow analysis of the lateral and longitudinal assembly kinetics of vimentin

Lovis Schween , N. Mücke , Stéphanie Portet , W. H. Goldmann , H. Herrmann , B. Fabry
bioRxiv 2022-06-09
5 citations

Impact of noise on the regulation of intracellular transport of intermediate filaments.

Stéphanie Portet , S. Étienne-Manneville , Cécile Leduc , J. Dallon
Journal of Theoretical Biology 2022-06-01
7 citations

A general mathematical model for the in vitro assembly dynamics of intermediate filament proteins.

N. Mücke , T. Wocjan , Marine Jacquier , H. Herrmann , Stéphanie Portet
Biophysical Journal 2022-02-01
5 citations